Rotenone (CAS number 83-79-4) is a colorless-to-red, odorless solid. In solution it is used as a broad-spectrum insecticide that works by inhibiting the transport of electrons in the respiration pathway.

It also kills fish and is used to eradicate exotic fish from their non-native habitats. It is toxic to humans and other mammals. However, it breaks down when exposed to sunlight and has a short lifetime (a week or less) in the environment.

Rotenone is produced by extraction from the roots, seeds, and leaves of certain tropical legumes.